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Showing 1–6 of 6 results
Advanced filters: Author: "Peter Rossing" Clear advanced filters

  • Increased urinary excretion of albumin and creatinine is associated with renal and cardiovascular events. Should the urinary albumin-to-creatinine ratio be considered a combination of two independent risk markers, or is it simply an easy way to obtain the same prognostic information as from a 24 h urine collection?

    • Peter Rossing
    News & Views
    Nature Reviews Nephrology
    Volume: 8, P: 320-321

  • Bardoxolone methyl showed promising results in initial studies in patients with type 2 diabetic kidney disease, but a phase III trial was terminated early in October 2012 due to adverse effects and increased mortality. Can adverse findings of analogues of bardoxolone methyl in an animal model explain the human findings?

    • Peter Rossing
    News & Views
    Nature Reviews Nephrology
    Volume: 9, P: 128-130

  • Low circulating levels of vitamin D metabolites were found to be associated with development of microalbuminuria in patients with type 1 diabetes mellitus from the DCCT/EDIC study. Could interventions aimed at improving vitamin D levels be a new option for the prevention of diabetic kidney disease?

    • Peter Rossing
    • Christel Joergensen
    News & Views
    Nature Reviews Endocrinology
    Volume: 9, P: 6-7

  • A new subclassification of diabetes based on quantitative traits, including age, body mass index, insulin resistance and β-cell function suggests five clusters with distinct phenotypes and prognoses. This approach may offer a novel way to classify diabetes by providing more information on risks and potential therapeutic strategies.

    • Peter Rossing
    News & Views
    Nature Reviews Nephrology
    Volume: 14, P: 355-356

  • In 2014, key studies in the field of diabetic nephropathy highlighted the importance of albuminuria as a predictor of cardiovascular risk and showed that the incidence of renal and cardiovascular complications is decreasing. Promising efficacy data were obtained with atrasentan, whereas a trial of bardoxolone methyl led to safety concerns.

    • Hans-Henrik Parving
    • Peter Rossing
    News & Views
    Nature Reviews Nephrology
    Volume: 11, P: 68-70