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Showing 1–7 of 7 results
Advanced filters: Author: "Philip Tinnefeld" Clear advanced filters
  • Super-resolution pMINFLUX microscopy is combined with FRET and enables co-tracking of two fluorophores without photoswitching.

    • Fiona Cole
    • Jonas Zähringer
    • Philip Tinnefeld
    Research
    Nature Photonics
    P: 1-7
  • Single-molecule fluorescence currently requires specialized imaging equipment due to the low signal of a single emitter. Here the authors introduce NanoAntennas with Cleared HOtSpots (NACHOS) to boost the signal sufficient for detection of a single emitter by a smartphone, opening the door to point-of-care applications.

    • Kateryna Trofymchuk
    • Viktorija Glembockyte
    • Philip Tinnefeld
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-8
  • Single-molecule detection commonly requires focused laser beams because of the small absorption cross-sections of dye molecules. Now, researchers have shown that thousands of dye molecules in nanoparticles can transfer light excitation to a single acceptor dye, enabling single-molecule detection at sunlight excitation power.

    • Guillermo P. Acuna
    • Philip Tinnefeld
    News & Views
    Nature Photonics
    Volume: 11, P: 616-618
  • The combination of a plasmonic nanoantenna and a nanoaperture has merged fluorescence enhancement and spatial confinement to enable single-molecule detection at biologically relevant concentrations.

    • Philip Tinnefeld
    News & Views
    Nature Nanotechnology
    Volume: 8, P: 480-482
  • An innovative marriage of techniques, combining the principles of common protein pull-down assays with single-molecule fluorescence microscopy, opens up new ways of visualizing cellular protein complexes. See Article p.484

    • Philip Tinnefeld
    News & Views
    Nature
    Volume: 473, P: 461-462