Rapid advances in techniques such as DNA sequencing and genome-wide-association studies have made a great impact on oncology research. In this comprehensive Review, the authors describe some of the most important molecular changes in different cancers that have been gleaned from these technologies, and have allowed earlier diagnosis and more appropriate treatment. The authors also highlight why the molecular pathology revolution is profound for cancer patients and the health-care system.
- Timothy J. R. Harris
- Frank McCormick