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Showing 1–4 of 4 results
Advanced filters: Author: "R Hayden" Clear advanced filters

    • Michael R. Hayden
    • Blair R. Leavitt
    • Peter Kirkpatrick
    Comments & Opinion
    Nature Reviews Drug Discovery
    Volume: 8, P: 17-18

  • How can we best reduce the risk of severe adverse reactions to marketed drugs? An international group of scientists argues that a global research network is needed to identify genetically at-risk populations.

    • Kathleen M. Giacomini
    • Ronald M. Krauss
    • Yusuke Nakamura
    Comments & Opinion
    Nature
    Volume: 446, P: 975-977

  • Here, the authors highlight how there are considerable similarities in the disease mechanisms and pathogenic pathways involved in Huntington's disease and Alzheimer's disease, and advocate that these shared mechanisms could be exploited as common therapeutic targets for drug development.

    • Dagmar E. Ehrnhoefer
    • Bibiana K. Y. Wong
    • Michael R. Hayden
    Reviews
    Nature Reviews Drug Discovery
    Volume: 10, P: 853-867

  • In this Review, Pouladi and colleagues critically examine the strengths and limitations of the currently available animal models of Huntington's disease. By doing so, they aim to facilitate animal model selection in future studies of this progressive neurodegenerative disorder.

    • Mahmoud A. Pouladi
    • A. Jennifer Morton
    • Michael R. Hayden
    Reviews
    Nature Reviews Neuroscience
    Volume: 14, P: 708-721