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Showing 1–2 of 2 results
Advanced filters: Author: "Ralf H. Adams" Clear advanced filters

  • The angiogenic switch, which leads to the activation of endothelial cell proliferation and the growth of new blood vessels, is a crucial step in tumorigenesis. A study now shows that this process is linked to a microRNA in endothelial cells (909–914). Blocking microRNAs may offer new avenues for antiangiogenesis therapy to treat cancer.

    • Hanna M Eilken
    • Ralf H Adams
    News & Views
    Nature Medicine
    Volume: 16, P: 853-854

  • Preosteoclasts give rise to bone-resorbing osteoclasts, which are crucial for skeletal homeostasis. A study now shows that preosteoclasts also contribute to bone formation by releasing platelet-derived growth factor-BB, which promotes bone vascularization and osteogenesis.

    • Anjali P. Kusumbe
    • Ralf H. Adams
    News & Views
    Nature Medicine
    Volume: 20, P: 1238-1240