Advances in understanding the biology of tumour progression and metastasis have clearly highlighted the importance of aberrant tumour metabolism. Although much progress has been made in understanding the somatic mutations and expression genomics behind these alterations in metabolism, the regulation of these processes by microRNAs (miRNAs) is only beginning to be appreciated. This Review presents a comprehensive summary of current knowledge of miRNA-mediated metabolic regulation in cancer, with a particular focus on pancreatic cancer.
- Pankaj K. Singh
- Randall E. Brand
- Kamiya Mehla
