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Showing 1–2 of 2 results
Advanced filters: Author: "Randall T. Moon" Clear advanced filters

  • The cytoplasmic and nuclear steps of the Wnt signalling pathway are fairly well understood. New insights into how secreted Wnt ligands stimulate receptor-mediated signalling have shown an unexpected diversity of Wnt receptors and further complexity in cellular responses.

    • Stephane Angers
    • Randall T. Moon
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 10, P: 468-477

  • This Review highlights the complexity and context-dependent roles of both β-catenin-dependent and β-catenin-independent WNT signalling pathways in cancer, as well as some of the ways in which WNT signalling might be targeted therapeutically.

    • Jamie N. Anastas
    • Randall T. Moon
    Reviews
    Nature Reviews Cancer
    Volume: 13, P: 11-26