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Showing 1–5 of 5 results
Advanced filters: Author: "Richard A. Gibbs" Clear advanced filters

  • The gorilla genome reveals that genetic similarities among humans and the apes are more complex than expected, and allows a fresh assessment of the evolutionary mechanisms that led to the primate species seen today. See Article p.169

    • Richard A Gibbs
    • Jeffrey Rogers
    News & Views
    Nature
    Volume: 483, P: 164-165

  • A new study reports large-scale systematic resequencing of the coding exons of the X chromosome in males with X-linked mental retardation (XLMR), illustrating the challenge of sorting through large amounts of benign variation in order to identify disease-causing sequence changes.

    • David L Nelson
    • Richard A Gibbs
    News & Views
    Nature Genetics
    Volume: 41, P: 510-512

  • The giant-panda genome is the first reported de novo assembly of a large mammalian genome achieved using next-generation sequencing methods. The feat reflects a trend towards ever-decreasing genome-sequencing costs.

    • Kim C. Worley
    • Richard A. Gibbs
    News & Views
    Nature
    Volume: 463, P: 303-304

  • It has been four years since the original publication of the draft sequence of the rat genome. Five groups are now working together to assemble, annotate and release an updated version of the rat genome. As the prevailing model for physiology, complex disease and pharmacological studies, there is an acute need for the rat's genomic resources to keep pace with the rat's prominence in the laboratory. In this commentary, we describe the current status of the rat genome sequence and the plans for its impending 'upgrade'. We then cover the key online resources providing access to the rat genome, including the new SNP views at Ensembl, the RefSeq and Genes databases at the US National Center for Biotechnology Information, Genome Browser at the University of California Santa Cruz and the disease portals for cardiovascular disease and obesity at the Rat Genome Database.

    • Simon N Twigger
    • Kim D Pruitt
    • Howard J Jacob
    Comments & Opinion
    Nature Genetics
    Volume: 40, P: 523-527

  • Whole-genome assemblies of humans and non-human primates are yielding data on the evolutionary origins of the human genome, as well as insights into genetic similarities and differences between species used as models for disease-related research. This Review discusses current knowledge and opportunities for comparative primate genomics created by recent advances in genome sequencing technologies.

    • Jeffrey Rogers
    • Richard A. Gibbs
    Reviews
    Nature Reviews Genetics
    Volume: 15, P: 347-359