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Advanced filters: Author: "Richard J. Maraia" Clear advanced filters
  • Postsynthetic modifications are widespread in genetic regulation. Trm9-mediated modification of the anticodon wobble base of specific tRNAs modulates expression of DNA damage response mRNAs in which cognate codons are unusually overrepresented. Thus, modification-dependent tRNA decoding activity is keyed to codon use in a genetic program.

    • Richard J Maraia
    • Nathan H Blewett
    • Mark A Bayfield
    News & Views
    Nature Chemical Biology
    Volume: 4, P: 162-164
  • Three structures of the enzyme RNA polymerase III, which is responsible for the synthesis of abundant short RNAs, reveal the specializations that make it an adept terminator and reinitiator of transcription. See Article p.231

    • Richard J. Maraia
    • Keshab Rijal
    News & Views
    Nature
    Volume: 528, P: 204-205