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Advanced filters: Author: "Robert Craigie" Clear advanced filters

  • Every machine is made of parts. But, as the new structure of the HIV integrase enzyme in complex with viral DNA shows, one could not have predicted from the individual parts just how this machine works.

    • Robert Craigie
    News & Views
    Nature
    Volume: 464, P: 167-168

  • HIV-1 and some other retroviruses can infect cells that are not dividing, so the viral DNA must cross the intact nuclear envelope to integrate into the host chromatin and persist. This Review teases apart the different threads of research to try and identify the mechanisms that underlie the nuclear entry of retroviruses.

    • Youichi Suzuki
    • Robert Craigie
    Reviews
    Nature Reviews Microbiology
    Volume: 5, P: 187-196