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Advanced filters: Author: "Rodger P McEver" Clear advanced filters

  • T cells interact with chemokines displayed on cells outside and inside blood vessels of the lymph node. New work shows that these chemokines exert distinct activation effects on T cell integrins depending on their mechanical environment.

    • Rodger P McEver
    • Cheng Zhu
    News & Views
    Nature Immunology
    Volume: 8, P: 1035-1037

  • Neutrophils and other cells secrete the pentraxin PTX3, which promotes innate immunity by binding to pathogens and activating complement. PTX3 can also limit neutrophil recruitment by inhibiting rolling on P-selectin in inflamed venules.

    • Rodger P McEver
    News & Views
    Nature Immunology
    Volume: 11, P: 282-284