The symptoms of malaria are associated with the erythrocytic phase ofPlasmodiumspp. infection, but the pre-erythrocytic (PE) phase, which is clinically silent, has long been of interest as a potential vaccination target. Robert Ménard and colleagues review how our understanding of the PE phase has changed over the past decade and how this in turn has informed our understanding of the host immune response.
- Robert Ménard
- Joana Tavares
- Rogerio Amino