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Showing 1–4 of 4 results
Advanced filters: Author: "Ron Diskin" Clear advanced filters

  • New World arenaviruses utilize the cellular transferrin receptor 1 (TfR1) to enter host cells. Here, the authors develop a TfR1-mimetic immunoadhesin, Arenacept, that targets viral spike complexes and exerts effective pan-reactive neutralization against pathogenic mammarenaviruses.

    • Hadas Cohen-Dvashi
    • Ron Amon
    • Ron Diskin
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-11

  • X-ray crystallography uncovers the structural basis of interaction between Lujo virus GP1 with its neuropilin-2 (NRP2) receptor.

    • Hadas Cohen-Dvashi
    • Itay Kilimnik
    • Ron Diskin
    Research
    Nature Microbiology
    Volume: 3, P: 1153-1160

  •  The structure of the complete native spike complex of Lassa virus reveals its membrane topology and the matriglycan-depended recognition of its α-dystroglycan cellular receptor.

    • Michael Katz
    • Jonathan Weinstein
    • Ron Diskin
    Research
    Nature
    Volume: 603, P: 174-179

  • The type-I fatty acid synthase (FAS-I) complex is essential for Mycobacterium tuberculosis (Mtb) and mediates the production of C26 fatty acids that are precursors for the synthesis of mycolic acids. Here the authors present the 3.3 Å resolution cryo-EM structure of Mtb FAS-I, which is of interest for tuberculosis drug development.

    • Nadav Elad
    • Szilvia Baron
    • Ron Diskin
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-6