Predicting the virulence of a particular bacterial strain is a complex task that currently cannot be achieved from genome sequence data alone. In this Opinion article, Massey and colleagues present a framework for the construction of a systems biology-based tool that they think could be used to predict virulence phenotypes fromStaphylococcus aureusgenomic sequences using existing technologies.
- Nicholas K. Priest
- Justine K. Rudkin
- Ruth C. Massey