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Advanced filters: Author: "Sarah A Teichmann" Clear advanced filters

  • A discussion of some of the challenges and promise of single-cell technology.

    • Xi Chen
    • J Christopher Love
    • Sarah A Teichmann
    Special Features
    Nature Biotechnology
    Volume: 34, P: 1111-1118

  • Fibroblast, epithelial and endothelial cells are more than just the scaffold of an organ — it emerges that they communicate with immune cells and are primed to launch organ-specific gene-expression programs for antiviral defence.

    • Tomás Gomes
    • Sarah A. Teichmann
    News & Views
    Nature
    Volume: 583, P: 206-207

  • High-throughput RNA sequencing (RNA-seq) is a powerful method for transcriptome-wide analysis that has recently been applied to single cells. This Review discusses the analytical and computational challenges of processing and analysing single-cell RNA-seq data, paying special consideration to differences relative to the analysis of RNA-seq data generated from bulk cell populations and discussing how single-cell-specific biological insights can be obtained.

    • Oliver Stegle
    • Sarah A. Teichmann
    • John C. Marioni
    Reviews
    Nature Reviews Genetics
    Volume: 16, P: 133-145