A key aim of personalized medicine is to optimize the prevention, diagnosis, and treatment of diseases by tailoring them to individual patient characteristics and genetics. In this Review, Henry Völzke and colleagues describe the methodological and statistical features of study design that will allow personalized medicine to be translated from a promising theoretical concept to a clinically beneficial, cost-effective reality in cardiovascular medicine.
- Henry Völzke
- Carsten O. Schmidt
- Heyo K. Kroemer
