Antiresorptive therapies, such as bisphosphonates, estrogens, selective estrogen receptor modulators, calcitonin and denosumab, are used to increase bone strength in individuals with osteoporosis. However, no single antiresorptive therapy is appropriate for all patients or clearly superior to other therapies. This Review describes the advances in our understanding of antiresorptive therapies and summarizes the benefits and risks associated with various drugs with an antiresorptive effect.
- Jian Sheng Chen
- Philip N. Sambrook