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Showing 1–3 of 3 results
Advanced filters: Author: "Shiv Srivastava" Clear advanced filters

  • The potential of the prostate cancer antigen 3 (PCA3) urine assay to aid prostate cancer diagnosis and minimize unnecessary biopsies has been extensively studied. Results from three recent studies that compared the performance of PCA3 with PSA underscore the advancement and future challenges for this new diagnostic biomarker.

    • George Leighton Lee
    • Albert Dobi
    • Shiv Srivastava
    News & Views
    Nature Reviews Urology
    Volume: 8, P: 123-124

  • Prostate cancer biology seems to be distinct among men of different ethnicities and races, as demonstrated by remarkable differences in the frequency ofERG oncogenic activation. In this Review, Sedarsky and colleagues discuss worldwide ERGalteration frequencies and consider how the data can be affected by variations in assay platforms and specimen types, as well as ethnic and geographical classifications, in order to realize the potential of precision medicine for men with prostate cancer.

    • Jason Sedarsky
    • Michael Degon
    • Albert Dobi
    Reviews
    Nature Reviews Urology
    Volume: 15, P: 125-131

  • Rosen and colleagues discuss some of the recently published and ongoing studies that have provided noteworthy insights into the expression of the ERG oncoprotein in prostate cancer. They describe the available monoclonal antibodies and consider the clinical potential of ERG protein detection in the diagnosis and prognosis of prostate cancer.

    • Philip Rosen
    • Isabell A. Sesterhenn
    • Albert Dobi
    Reviews
    Nature Reviews Urology
    Volume: 9, P: 131-137