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Showing 1–3 of 3 results
Advanced filters: Author: "Simon J. Davis" Clear advanced filters

  • Interleukin 2 (IL-2) and IL-15 use receptors with the same signaling subunits. New structural data show that the signaling complexes they form are topologically nearly identical, which suggests that other factors are responsible for the distinct signaling properties of these complexes.

    • Shinji Ikemizu
    • Mami Chirifu
    • Simon J Davis
    News & Views
    Nature Immunology
    Volume: 13, P: 1141-1142

  • Acute inhibition of the regulatory kinase Csk reveals additional checkpoints for full activation of thymocytes via the T cell antigen receptor.

    • Michael L Dustin
    • Simon J Davis
    News & Views
    Nature Immunology
    Volume: 15, P: 136-137

  • Recent advances in microscopy have enabled imaging of cell surface receptors at ever higher resolutions. A report using the latest technology now provides evidence that the T cell antigen receptor and the adaptor Lat are confined to small islands, which cluster together after triggering of the T cell antigen receptor.

    • P Anton van der Merwe
    • Paul D Dunne
    • Simon J Davis
    News & Views
    Nature Immunology
    Volume: 11, P: 51-52