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Showing 1–2 of 2 results
Advanced filters: Author: "Sophie Hambleton" Clear advanced filters

  • Zinc is important for normal immunity but its mechanistic actions are poorly understood. Hambleton and colleagues identify defects in Zn2+ transport that underpin a novel human immunodeficiency characterized by loss of mature B cells.

    • Consuelo Anzilotti
    • David J. Swan
    • Sophie Hambleton
    Research
    Nature Immunology
    Volume: 20, P: 350-361

  • Much insight into the workings of the immune system has been garnered from studying patients with primary immunodeficiencies. This article describes the recent discovery of human dendritic cell deficiencies and explains the lessons we can learn from these syndromes.

    • Matthew Collin
    • Venetia Bigley
    • Sophie Hambleton
    Reviews
    Nature Reviews Immunology
    Volume: 11, P: 575-583