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Showing 1–8 of 8 results
Advanced filters: Author: "Stefan H. E. Kaufmann" Clear advanced filters

  • Lab luminaries jostle with consumptive cultural icons in a vivid history of tuberculosis, finds Stefan H. E. Kaufmann.

    • Stefan H. E. Kaufmann
    Books & Arts
    Nature
    Volume: 490, P: 477-478

  • Many factors affect the severity of tuberculosis in infected individuals. Among these are the genetic make-up of the bacterial strain, that of the host, and the interplay between the two.

    • Stefan H. E. Kaufmann
    News & Views
    Nature
    Volume: 453, P: 295-296

  • New tuberculosis vaccines are urgently needed to reduce the threat of this devastating disease. An approach consisting of a fusion protein of three tuberculosis antigens provides significant protection in before- and after-exposure challenge mouse models, representing a crucial step forward in tackling tuberculosis in latently infected individuals (pages 189–194).

    • Stefan H E Kaufmann
    News & Views
    Nature Medicine
    Volume: 17, P: 159-160

  • Host-directed therapy (HDT) aims to interfere with host cell factors that are required by a pathogen for replication or persistence. In this Review, Kaufmannet al. describe recent progress in the development of HDTs for the treatment of viral and bacterial infections and the challenges in bringing these approaches to the clinic.

    • Stefan H. E. Kaufmann
    • Anca Dorhoi
    • Ralf Bartenschlager
    Reviews
    Nature Reviews Drug Discovery
    Volume: 17, P: 35-56