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Advanced filters: Author: "Stephanie Gras" Clear advanced filters
  • Mutations within immunological epitope containing regions of influenza A virus can impair the established immune response between influenza strains and could impact rational vaccine design. Here Grant et al. examine the presence, structural impact and cross reactivity of two human immunodominant influenza epitope variants.

    • Emma J. Grant
    • Tracy M. Josephs
    • Katherine Kedzierska
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-16
  • T cell cross-reactivity enables the immune system to recognize a large array of peptides. A new study shows that T cells can achieve cross-recognition by using the remarkable plasticity of peptides, through flipping the peptide out of the binding cleft.

    • Stephanie Gras
    News & Views
    Nature Chemical Biology
    Volume: 14, P: 905-906