The coronary collateral circulation protects the myocardium when blood flow is reduced because of an occlusion. In this Review, Zimarino and colleagues discuss the development of collateral vessels through tissue remodelling. Collaterals and their underlying adaptative mechanisms are clinically important to modern interventional cardiology.
- Marco Zimarino
- Mariangela D'Andreamatteo
- Raffaele De Caterina
