The mast cell–derived phospholipase PLA2G3 and fibroblast prostaglandin synthase contribute to a mast cell–fibroblast paracrine axis dependent on the prostaglandin PGD2 and its receptor DP1 that can enhance the maturation and mediator secretion of mast cells.
- Philipp Starkl
- Thomas Marichal
- Stephen J Galli