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Showing 1–2 of 2 results
Advanced filters: Author: "Stephen J. Nicholls" Clear advanced filters

  • A new report has demonstrated the combined use of optical coherence tomography and molecular imaging within human coronary arteries. This combination provides a unique opportunity to look at plaque from a view not previously possible, opening the field for greater understanding of plaque biology in research and clinical practice.

    • Peter J. Psaltis
    • Stephen J. Nicholls
    News & Views
    Nature Reviews Cardiology
    Volume: 13, P: 253-255

  • The challenge of predicting potential efficacy of anti-atherosclerotic drugs before the completion of long-term trials with endpoints such as mortality has stimulated efforts to develop intermediate measures of efficacy. Nissen and colleagues describe how intravascular ultrasound can be applied to the serial assessment of atheroma burden in response to treatment, which has resulted in its emergence as a key technology in the evaluation and approval of novel drugs.

    • Stephen J. Nicholls
    • Ilke Sipahi
    • Steven E. Nissen
    Reviews
    Nature Reviews Drug Discovery
    Volume: 5, P: 485-492