Genetic, biochemical, ultrastructural and physiological studies of mouse mutants have crucially advanced our understanding of the molecular mechanisms of hearing. A detailed picture is emerging of the protein complexes that are responsible for the growth and cohesion of the stereocilia bundle — a complex subcellular structure at the core of the auditory apparatus.
- Steve D. M. Brown
- Rachel E. Hardisty-Hughes
- Philomena Mburu
