Genome-wide analyses have identified a number of novel microRNAs (miRNAs) related to immunological and pathological changes in the kidney. In this Review, the authors describe the various purported roles of these miRNAs in IgA nephropathy, including in the aberrant glycosylation of IgA1that has a central pathogenetic role in the early phase of this disease.
- Cheuk-Chun Szeto
- Philip K.-T. Li