In the past few years, basic research and epidemiological studies have provided a wealth of new data on renal prognosis following acute kidney injury (AKI) and the potential association of AKI with incident chronic kidney disease (CKD), progression of CKD, and incident end-stage renal disease. The authors of this Review describe these findings and discuss the possible mechanisms by which AKI might lead to CKD or CKD progression.
- Kelvin C. W. Leung
- Marcello Tonelli
- Matthew T. James