Optic neuritis is an inflammatory optic neuropathy that is frequently—but not always—associated with multiple sclerosis (MS). Despite recent developments in laboratory, imaging and electrophysiological techniques, no consensus guidelines have yet been formulated for the diagnostic work-up in patients presenting with optic neuritis. In this Review, Petzold and colleagues contribute to the development of such a consensus by proposing an investigation protocol for optic neuritis.
- Axel Petzold
- Mike P. Wattjes
- Gordon T. Plant