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Showing 1–2 of 2 results
Advanced filters: Author: "The RGASP Consortium" Clear advanced filters

  • The RGASP consortium compared 25 RNA-seq analysis programs in their ability to identify exons, reconstruct transcripts and quantify expression levels. Assembly of isoforms and their expression levels in higher eukaryotes remains a challenge.

    • Tamara Steijger
    • Josep F Abril
    • Paul Bertone
    ResearchOpen Access
    Nature Methods
    Volume: 10, P: 1177-1184

  • Authors compare RNA-seq aligners on mouse and human data sets using benchmarks such as alignment yield, splice junction accuracy and suitability for transcript reconstruction. The work highlights the strength of each program and discusses outstanding needs in RNA-seq analysis.

    • Pär G Engström
    • Tamara Steijger
    • Paul Bertone
    ResearchOpen Access
    Nature Methods
    Volume: 10, P: 1185-1191