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Advanced filters: Author: "Thomas Hoffmann" Clear advanced filters

  • Thomas Hoffmann, Neil Risch and colleagues use longitudinal electronic health records from almost 100,000 individuals to conduct genome-wide association studies for blood pressure measurements. They find new significant loci that replicate in independent cohorts and can double the variance explained by using multiple blood pressure data points.

    • Thomas J Hoffmann
    • Georg B Ehret
    • Neil Risch
    Research
    Nature Genetics
    Volume: 49, P: 54-64

  • Genome-wide association analysis using electronic health record data from >94,000 individuals identifies loci associated with plasma lipid concentrations. Longitudinal measurements allow for the calculation of genetic risk scores and increase the variance explained.

    • Thomas J. Hoffmann
    • Elizabeth Theusch
    • Neil Risch
    Research
    Nature Genetics
    Volume: 50, P: 401-413