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  • Animals sense light and chemical signals through proteins called G-protein-coupled receptors. The crystal structure of one such receptor in complex with a G-protein fragment shows how these receptors are activated.

    • Thue W. Schwartz
    • Wayne L. Hubbell
    News & Views
    Nature
    Volume: 455, P: 473-474
  • G-protein-coupled receptors initiate signalling pathways by forming complexes with agonist molecules and G proteins. The first crystal structure of such a complex is both reassuring and provocative. See Article p.549 & Letter p.611

    • Thue W. Schwartz
    • Thomas P. Sakmar
    News & Views
    Nature
    Volume: 477, P: 540-541