Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–5 of 5 results
Advanced filters: Author: "Tom Curran" Clear advanced filters

  • Research into basic developmental biology has frequently yielded insights into cancer biology. This is particularly true for the Hedgehog (HH) pathway, and both naturally occurring and synthetic inhibitors of HH signalling show great promise. However, it remains unclear how many cancers will ultimately benefit from these new, molecularly targeted therapies.

    • Jessica M. Y. Ng
    • Tom Curran
    Reviews
    Nature Reviews Cancer
    Volume: 11, P: 493-501

  • The poet Archilochus wrote “The fox has many tricks, and the hedgehog one great one”. Yet a signalling-pathway namesake of hedgehog may have two great tricks that could be exploited for cancer therapy.

    • Tom Curran
    • Jessica M. Y. Ng
    News & Views
    Nature
    Volume: 455, P: 293-294

  • The visualization of protein complexes in living cells enables the investigation of molecular interactions in their native environment. Bimolecular fluorescence complementation analysis has been used to visualize protein interactions and modifications in different cell types and species.

    • Tom K. Kerppola
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 7, P: 449-456