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Showing 1–6 of 6 results
Advanced filters: Author: "Tore K. Kvien" Clear advanced filters

  • Clinical guidelines and recommendations, as well as clinicians and patients, consider non-pharmacological modalities to be the mainstay of treatment for osteoarthritis (OA). Despite this consensus in opinion, however, the evidence base for the non-pharmacological management of hand and hip OA continues to lag far behind that for knee OA, which suggests that more research is required to optimize the management of hand and hip OA.

    • Kåre B. Hagen
    • Geir Smedslund
    • Tore K. Kvien
    Reviews
    Nature Reviews Rheumatology
    Volume: 5, P: 517-519

  • Since the 1970s, rheumatologists have increasingly reported seeing patients with milder onset of rheumatoid arthritis and a less-severe disease course than in preceding decades. Are these improvements attributable to earlier diagnosis, better therapeutic options, or simply a milder natural disease course? Uhlig and Kvien review the evidence for the perceived decrease in disease severity and discuss the potential reasons for this phenomenon.

    • Till Uhlig
    • Tore K. Kvien
    Reviews
    Nature Reviews Rheumatology
    Volume: 5, P: 461-464

  • Radiographic joint damage is strongly associated with disability in patients with rheumatoid arthritis, but the relative importance of the two major measures of radiographic damage—bone erosions and joint space narrowing—is not clearly understood. In this article, the authors discuss this issue, and describe how imaging modalities that allow detailed visualization of cartilage might lead to improved understanding.

    • Siri Lillegraven
    • Désirée van der Heijde
    • Espen A. Haavardsholm
    Reviews
    Nature Reviews Rheumatology
    Volume: 8, P: 117-120

  • No increased risk of adverse pregnancy outcome has been reported in patients with inflammatory arthropathies treated with tumor necrosis factor antagonists. More data are required, however, before firm conclusions can be drawn regarding the safety of these agents during pregnancy, childbirth and lactation, as outlined in this article.

    • Johan F Skomsvoll
    • Marianne Wallenius
    • Tore K Kvien
    Reviews
    Nature Clinical Practice Rheumatology
    Volume: 3, P: 156-164