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Showing 1–3 of 3 results
Advanced filters: Author: "Tracey A Rouault" Clear advanced filters

  • Recent studies suggest that iron-sulfur (Fe-S) proteins may be unexpectedly abundant and functionally diverse in mammalian cells, but their identification still remains difficult. The use of informatics along with traditional spectroscopic analyses could be key to discovering new Fe-S proteins and validating their functional roles.

    • Tracey A Rouault
    Comments & Opinion
    Nature Chemical Biology
    Volume: 11, P: 442-445

  • Intricate mechanisms regulate iron homeostasis in the CNS. In this Review, Rouault considers the role of brain iron accumulation in several common neurodegenerative disorders and discusses 'neurodegeneration with brain iron accumulation' diseases that are associated with specific genetic mutations.

    • Tracey A. Rouault
    Reviews
    Nature Reviews Neuroscience
    Volume: 14, P: 551-564

  • New insights into how iron–sulphur (Fe–S) clusters are incorporated into proteins, particularly the discovery of a role for Leu-Tyr-Arg motifs in Fe–S recipient proteins, are shedding light on the fundamental roles of Fe–S proteins in mammalian cells.

    • Tracey A. Rouault
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 16, P: 45-55