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Showing 1–3 of 3 results
Advanced filters: Author: "Ulrich von Andrian" Clear advanced filters

  • Vitamins have long been known to have an effect on the immune system. In this Review, the authors describe the effects of vitamins, particularly of vitamins A and D, on immune cells, and discuss how vitamins or their analogues might be applied for the therapy of immune-mediated diseases.

    • J. Rodrigo Mora
    • Makoto Iwata
    • Ulrich H. von Andrian
    Reviews
    Nature Reviews Immunology
    Volume: 8, P: 685-698

  • Thrombosis is the most frequent cause of mortality worldwide. In this Review, the authors propose that thrombosis might also have a conserved physiological role in immune defence via a process termed immunothrombosis. However, if uncontrolled, immunothrombosis facilitates pathological clot formation.

    • Bernd Engelmann
    • Steffen Massberg
    Reviews
    Nature Reviews Immunology
    Volume: 13, P: 34-45

  • Although studies in 2D cell culture systems have provided great insights into the biology and pathogenesis of HIV-1 infection, such studies cannot account for many aspects of host physiology that affect HIV-1in vivo. Fackler et al. discuss the development and application of more integrative studies, including organotypic 3D culture systems, small-animal models and advanced live-cell imaging, and the impact of such studies on our understanding of the mechanisms of HIV-1 spread.

    • Oliver T. Fackler
    • Thomas T. Murooka
    • Thorsten R. Mempel
    Reviews
    Nature Reviews Microbiology
    Volume: 12, P: 563-574