By integrating discussion of responses to HLA and non-HLA donor antigens in transplantation, and fetomaternal microchimerism, Pierre Ronco and colleagues have produced a clear and concise overview of alloimmune processes underlying nephropathy of both grafted and native kidneys. The article describes the authors' discovery of a novel form of alloimmunization which causes congenital embranous nephropathy—transfer of antibodies against neutral endopeptidase from mother to fetus.
- Pierre Ronco
- Hanna Debiec
- Vincent Guigonis
