The use of probiotics is increasing in popularity for both the prevention and treatment of a variety of diseases; however, the specific immune and physiological effects of probiotics in health and disease have not been fully elucidated. This Review considers recent advances in clinical trials of probiotics for intestinal disorders. An overview ofin vitro and in vivoresearch related to potential mechanisms of action of various probiotic formulations is also considered.
- Mélanie G. Gareau
- Philip M. Sherman
- W. Allan Walker
