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Advanced filters: Author: "Walter P. Maksymowych" Clear advanced filters
  • Clinicians now have the therapies and outcome tools to implement treat-to-target strategies aimed at achieving and maintaining adequate function and control of symptoms in spondyloarthritis and psoriatic arthritis. However, validation of surrogate markers of structural progression is a prerequisite for treat-to-target strategies aimed at improving long-term outcomes such as joint damage.

    • Walter P. Maksymowych
    News & Views
    Nature Reviews Rheumatology
    Volume: 9, P: 507-508
  • Advances in 2012 have helped to solve several established mysteries in spondyloarthritis (SpA)—why T-cell-directed therapies have not delivered the expected efficacy and how the IL-23–IL-17 cytokine axis is linked to the specific pathology of SpA. The opportunity to influence disease progression at inflammatory lesions using anti-TNF agents may be fleeting.

    • Walter P. Maksymowych
    News & Views
    Nature Reviews Rheumatology
    Volume: 9, P: 72-74