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Advanced filters: Author: "William C. Earnshaw" Clear advanced filters

  • William Earnshaw describes the events that led to the discovery and cloning of the first kinetochore proteins 30 years ago using autoimmune sera from patients with scleroderma-spectrum disease. He also discusses our current appreciation of the complexity of this remarkable structure.

    • William C. Earnshaw
    Comments & Opinion
    Nature Reviews Molecular Cell Biology
    Volume: 16, P: 443-449

  • The chromosomal passenger complex (CPC), which is formed by inner centromere protein (INCENP), borealin, survivin and Aurora B kinase, targets to different locations at different times during mitosis. As it regulates key events at each of these locations, the CPC can be considered as a master regulator of mitosis.

    • Mar Carmena
    • Michael Wheelock
    • William C. Earnshaw
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 13, P: 789-803