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Showing 1–6 of 6 results
Advanced filters: Author: "Winfried Denk" Clear advanced filters

  • In recent decades, advances in technology have enabled the structure of the nervous system to be dissected in greater detail than ever before. In this Opinion article, Denk and colleagues outline why structural information is so important for our understanding of the function of neural circuits and describe new tools and approaches that are improving the structural information that we can acquire.

    • Winfried Denk
    • Kevin L. Briggman
    • Moritz Helmstaedter
    Reviews
    Nature Reviews Neuroscience
    Volume: 13, P: 351-358

  • A method for staining and embedding the entire mouse brain for electron microscopy is reported. The method results in uniform myelin staining and will allow reconstructions of myelinated long-range axons using serial block-face electron microscopy.

    • Shawn Mikula
    • Jonas Binding
    • Winfried Denk
    Research
    Nature Methods
    Volume: 9, P: 1198-1201

  • Repeated imaging of the same individual neuron for over a year in mice allows the authors of a new study in this issue to show that presynaptic axon terminals become progressively more stable as the animals age, changing little after 6 to 12 months.

    • Winfried Denk
    News & Views
    Nature Neuroscience
    Volume: 6, P: 908-909

  • Advances in cellular imaging have been crucial for improving our understanding of many aspects of neuroscience. Kerr and Denk describe how sophisticated optical imaging techniques allow us to image activity in single neurons or neuron populations in living animals.

    • Jason N. D. Kerr
    • Winfried Denk
    Reviews
    Nature Reviews Neuroscience
    Volume: 9, P: 195-205