Corticotropin-releasing factor (CRF) and urocortins have traditionally been proposed to promote stress and stress recovery, respectively. However, recent findings suggest that this view is overly simplistic. Chen and colleagues review evidence showing that CRF-receptor signalling is region- and cell type-specific and influenced by the individual's experience.
- Marloes J. A. G. Henckens
- Jan M. Deussing
- Alon Chen