Cryptococcus neoformansis generally considered to be an opportunistic pathogen of immunocompromised individuals. However, as discussed here, this view has been challenged by recent evidence of specialized host–pathogen interactions, and by the emergence of the related speciesCryptococcus gattiias a primary pathogen of immunocompetent populations.
- James W. Kronstad
- Rodgoun Attarian
- Joyce Wang
