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Showing 1–3 of 3 results
Advanced filters: Author: "Xinzhong Dong" Clear advanced filters

  • The sensation of touch-evoked itch is common in people who have chronic itch conditions. Evidence in mice now suggests that the mechanoreceptor protein Piezo1 underlies this sensation.

    • Taylor Follansbee
    • Xinzhong Dong
    News & Views
    Nature
    Volume: 607, P: 36-37

  • A new study shows that astrocytes are involved in the development of chronic itch in a mouse model. This is dependent on upregulation of lipocalin 2 (LCN2) by the transcription factor STAT-3 and astrogliosis.

    • Dustin Green
    • Xinzhong Dong
    News & Views
    Nature Medicine
    Volume: 21, P: 841-842

  • Itch — the sensation that induces the desire to scratch — results from activity in a subset of nociceptors, all of which also respond to painful stimuli. LaMotte and colleagues describe the studies that have begun to pinpoint the molecular transducers and neural pathways that transmit itch and the coding mechanisms that distinguish it from pain.

    • Robert H. LaMotte
    • Xinzhong Dong
    • Matthias Ringkamp
    Reviews
    Nature Reviews Neuroscience
    Volume: 15, P: 19-31