The antithyroid drug propylthiouracil has been recognized to cause antineutrophil cytoplasmic antibody-associated vasculitis (AAV). This disease shares some characteristics with primary AAV although important differences do exist. The authors of this Review discuss the pathogenesis, risk factors, diagnosis and treatment of propylthiouracil-induced AAV and also outline the similarities and differences between propylthiouracil-induced AAV and primary AAV.
- Min Chen
- Ying Gao
- Ming-Hui Zhao