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Showing 1–4 of 4 results
Advanced filters: Author: "Yosef Gruenbaum" Clear advanced filters

  • The SUN-domain family of nuclear envelope proteins interacts with KASH-domain proteins, which are also nuclear envelope proteins, to form 'bridges' across the inner and outer nuclear membranes. SUN-domain proteins are now proposed to provide a mechanical connection between the nucleoskeleton and the cytoskeleton.

    • Yonatan B. Tzur
    • Katherine L. Wilson
    • Yosef Gruenbaum
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 7, P: 782-788

  • Two commonly prescribed drugs, statins and aminobisphosphonates, may be helpful in combating the rare aging disorder, Hutchinson-Gilford progeria syndrome (pages 767–772).

    • Eran Meshorer
    • Yosef Gruenbaum
    News & Views
    Nature Medicine
    Volume: 14, P: 713-715

  • Progerin, a mutated form of lamin A, causes the premature ageing disease Hutchinson-Gilford progeria syndrome and is also involved in normal ageing. Progerin accumulation leads to distinct chromatin-related defects and the NURD complex appears to affect ageing-related chromatin defects.

    • Eran Meshorer
    • Yosef Gruenbaum
    News & Views
    Nature Cell Biology
    Volume: 11, P: 1176-1177

    • Yosef Gruenbaum
    • Ayelet Margalit
    • Katherine L. Wilson
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 6, P: 21-31