A new method is used to selectively protect individual hydroxyl groups of a monosaccharide. Hundreds of building blocks have been efficiently prepared starting from D-glucose, and the iterative coupling of these building blocks enabled assembly of a library of oligosaccharides based on the influenza virus-binding trisaccharide.
- Cheng-Chung Wang
- Jinq-Chyi Lee
- Shang-Cheng Hung