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Showing 1–50 of 4938 results

  • A new study captures nearly the full repertoire of primate natural behaviour and reveals that highly distributed cortical activity maintains multifaceted dynamic social relationships.

    • Jake Rogers
    Research Highlights
    Nature Reviews Neuroscience
    P: 1

  • The main direction of motor skill-specific information between rat primary motor cortex and dorsolateral striatum is shown to switch from cortex-predominant before learning to striatum-predominant after learning.

    • Sian Lewis
    Research Highlights
    Nature Reviews Neuroscience
    P: 1

    • Juan Carlos López
    Research Highlights
    Nature Reviews Neuroscience
    Volume: 3, P: 171

  • A large network of brain regions is involved in salient distractor processing.

    • Isobel Leake
    Research Highlights
    Nature Reviews Neuroscience
    P: 1

  • The synaptic protein SynGAP exerts its effects on synaptic plasticity via a structural role rather than its GTPase-activating protein activity.

    • Darran Yates
    Research Highlights
    Nature Reviews Neuroscience
    Volume: 25, P: 287

  • One of the long-term sequelae associated with SARS-CoV-2 infection is ‘brain fog’, which is shown in this study to be linked to systemic inflammation and leakiness of the blood–brain barrier.

    • Sian Lewis
    Research Highlights
    Nature Reviews Neuroscience
    Volume: 25, P: 287

  • Neurons in the mouse subiculum encode concave and convex geometrical environmental features.

    • Katherine Whalley
    Research Highlights
    Nature Reviews Neuroscience
    Volume: 25, P: 287

  • Innate fear-like responses are thought to involve the amygdala, but here a tetra-synaptic pathway is identified that mediates odour-evoked innate fear in mice.

    • Sian Lewis
    Research Highlights
    Nature Reviews Neuroscience
    Volume: 25, P: 287

  • Populations of neurons in the mouse hippocampus use distinct representational strategies to encode familiarity and episodic social memory.

    • Katherine Whalley
    Research Highlights
    Nature Reviews Neuroscience
    Volume: 25, P: 210

  • Blood pressure pulsations modulate the activity of neurons in the rodent olfactory bulb via the mechanosensitive ion channel PIEZO2

    • Katherine Whalley
    Research Highlights
    Nature Reviews Neuroscience
    Volume: 25, P: 210

  • Many cognitive functions rely on the ability to link distinct but related memories, while retaining the capacity to recall the individual details of the linked memories. Inokuchi and colleagues describe evidence that memory linking involves engram overlap and discuss the mechanisms that regulate this process.

    • Ali Choucry
    • Masanori Nomoto
    • Kaoru Inokuchi
    Reviews
    Nature Reviews Neuroscience
    P: 1-18

  • The developmental colonization of the brain by microglial progenitors and establishment of microglial cell identity set the stage for microglial function in the adult. Barry-Carroll and Gomez-Nicola describe the mechanisms that regulate the development of microglia, including their origins, infiltration and colonization of the brain, proliferation and fate determination.

    • Liam Barry-Carroll
    • Diego Gomez-Nicola
    Reviews
    Nature Reviews Neuroscience
    P: 1-14

  • Many brain areas support complex language processing behaviours. In this Review, Fedorenko et al. disentangle the ‘core’ language system as functionally distinct from the perceptual and motor brain areas and knowledge and reasoning systems it closely interacts with during language comprehension and production.

    • Evelina Fedorenko
    • Anna A. Ivanova
    • Tamar I. Regev
    Reviews
    Nature Reviews Neuroscience
    Volume: 25, P: 289-312

  • In mice, a subset of neurons in the dorsomedial hypothalamus control sympathetic nervous system signalling to adipose tissue and are dysregulated with age; activating these neurons prolongs lifespan and slows the decline in physical activity associated with ageing.

    • Joseph Willson
    Research Highlights
    Nature Reviews Neuroscience
    Volume: 25, P: 141

  • A study analyses the nanotopography of presynaptic calcium channels and release sensors and the degree of their coupling during maturation of an inhibitory synapse.

    • Lisa Heinke
    Research Highlights
    Nature Reviews Neuroscience
    Volume: 25, P: 141

  • Parkinson disease (PD) has been linked to dysfunction in a number of key intracellular signalling pathways that contribute to disease pathology. Coukos and Krainc describe the physiological functions of a selection of PD-linked proteins and their convergent effects on mitochondrial, lysosomal and synaptic dysfunction in PD.

    • Robert Coukos
    • Dimitri Krainc
    Reviews
    Nature Reviews Neuroscience
    P: 1-21

  • Around 10% of individuals with frontotemporal lobar dementia have amyloid filament inclusions that lack tau and TDP-43 and were thought to contain the protein FUS, but are found instead to contain the FUS homologue TAF15.

    • Sian Lewis
    Research Highlights
    Nature Reviews Neuroscience
    Volume: 25, P: 78

  • A study indicates that different mechanisms of ATP production predominate in different cellular subcompartments in neurons.

    • Darran Yates
    Research Highlights
    Nature Reviews Neuroscience
    Volume: 25, P: 142

  • Cytoplasmic mislocalization of TDP-43 in neurodegenerative disease affects mRNA maturation and protein levels of stathmin-2, leading to a reduction in axon diameter and tearing of outer myelin layers and thereby disrupting neuronal function.

    • Lisa Heinke
    Research Highlights
    Nature Reviews Neuroscience
    Volume: 25, P: 78

  • Pathological compulsive behaviour is a potential transdiagnostic symptom of several neuropsychiatric disorders. In this Review, Robbins et al. examine the psychological basis of compulsions and compulsivity and their underlying neural circuitry, focused on fronto-striatal systems implicated in goal-directed behaviour and habits.

    • Trevor W. Robbins
    • Paula Banca
    • David Belin
    Reviews
    Nature Reviews Neuroscience
    Volume: 25, P: 313-333

  • A study in mice identifies formin 2 as a regulator of axon regeneration and a potential target for promoting nerve repair after peripheral nerve injury.

    • Darran Yates
    Research Highlights
    Nature Reviews Neuroscience
    Volume: 25, P: 142

  • A mark test of self-recognition in mice reveals that self-responding ventral CA1 neurons underlie mirror-induced self-directed behaviour and are shaped by social experience with conspecifics.

    • Jake Rogers
    Research Highlights
    Nature Reviews Neuroscience
    Volume: 25, P: 79

  • Increased levels of matrix metalloproteinase 8, expressed by circulating myeloid cells, may have a role in stress-induced changes in social behaviour in mice.

    • Darran Yates
    Research Highlights
    Nature Reviews Neuroscience
    Volume: 25, P: 209

  • A small population of neurons in the mouse brainstem coordinate sound production and volume control during vocalizations.

    • Katherine Whalley
    Research Highlights
    Nature Reviews Neuroscience
    Volume: 25, P: 78

  • In mice, specific pools of adult neural stem cells are recruited during pregnancy to support postpartum maternal behaviour.

    • Katherine Whalley
    Research Highlights
    Nature Reviews Neuroscience
    Volume: 25, P: 78

  • In mice, localized mutant APP expression in the CA3 hippocampal region leads to progressive network dysfunction and hippocampus-dependent memory deficits.

    • Darran Yates
    Research Highlights
    Nature Reviews Neuroscience
    Volume: 25, P: 4

  • Ongoing systemic and neurocognitive impairments that continue in a subset of individuals after infection with SARS-CoV-2 infection are found to be associated with reduced serotonin levels.

    • Sian Lewis
    Research Highlights
    Nature Reviews Neuroscience
    Volume: 25, P: 4

    • Sian Lewis
    Amendments and Corrections
    Nature Reviews Neuroscience
    Volume: 12, P: 544