Applied immunology articles within Nature Materials

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• News & Views | 02 March 2023

  Immunostimulatory nanoparticles go viral

  A polymeric nanoparticle adjuvant containing a Toll-like receptor 7 agonist elicits broad protection against viral challenges.

  • Jorge Huete-Carrasco
  •  & Ed C. Lavelle

• News & Views | 20 December 2022

  Towards a universal flu vaccine

  • Cristina Lo Giudice

• Editorial | 31 May 2022

  Materials at the heart of the COVID-19 pandemic

  Materials scientists have played a key role in the global response to the COVID-19 pandemic from the development of vaccines and diagnostic tools to the rapid prototyping of ventilators.

• Comment | 23 July 2020

  Next-generation vaccine platforms for COVID-19

  Consensus among experts is that only an effective COVID-19 vaccine will end the pandemic. This Comment focuses on how this pandemic has accelerated the development of vaccine platforms distinct from classical vaccines; these novel platforms may also increase the response time when new viruses emerge in the future.

  • Debby van Riel
  •  & Emmie de Wit

• News & Views | 23 July 2020

  Long-acting antiretroviral therapy

  Nanoformulations of cabotegravir prodrugs have been developed to prolong the pharmacokinetics of the antiretroviral agent. They can be present in the plasma of mice and non-human primates for a year following a single injection.

  • Vicente Soriano
  • , Pablo Barreiro
  •  & Carmen de Mendoza

• Article | 19 August 2019

  Hyaluronic acid–bilirubin nanomedicine for targeted modulation of dysregulated intestinal barrier, microbiome and immune responses in colitis

  Imbalance of the gut microbiome has been implicated in numerous human diseases. Nanoparticles have now been designed to target colitis by modulating the gut microbiome, local innate immune response and restoration of the intestinal barrier function.

  • Yonghyun Lee
  • , Kohei Sugihara
  •  & James J. Moon

• News & Views | 22 January 2019

  Next-generation malarial vaccines

  A vaccine platform developed from a synthetic polymeric glyco-adjuvant and reversibly conjugated to an antigen was shown to target dendritic cells leading to cellular and humoral immune response against malaria.

  • Yvette van Kooyk

• Letter | 05 March 2018

  A facile approach to enhance antigen response for personalized cancer vaccination

  A strategy to enhance antigen immunogenicity is shown using polyethyleneimine adsorbed on mesoporous silica microrod vaccine as a platform for neoantigens, supporting potent humoral immune response and inhibition of tumour growth following vaccination.

  • Aileen Weiwei Li
  • , Miguel C. Sobral
  •  & David J. Mooney

• News & Views | 23 January 2018

  Softness makes it better

  An effective adjuvant for the induction of humoural and cellular immunity is achieved by a Pickering emulsion formulation that allows pliability and mobility of loaded antigens.

  • Herman F. Staats
  •  & David J. Burkhart