Computational biophysics articles within Nature Materials

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  • Article |

    Viscoelasticity is a universal mechanical feature of the extracellular matrix. Here the authors show that the extracellular matrix viscoelasticity guides tissue growth and symmetry breaking, a fundamental process in morphogenesis and oncogenesis.

    • Alberto Elosegui-Artola
    • , Anupam Gupta
    •  & David J. Mooney

  • Article |

    Directed cell movement known as durotaxis, typically associated with cellular migration in response to a substrate gradient of increasing stiffness, is now shown to also occur in the opposite direction, following a gradient of decreasing stiffness.

    • Aleksi Isomursu
    • , Keun-Young Park
    •  & David J. Odde

  • Article |

    A mechanism of cell response to localized tension shows that syndecan-4 synergizes with EGFR to elicit a mechanosignalling cascade that leads to adaptive cell stiffening through PI3K/kindlin-2 mediated integrin activation.

    • Antonios Chronopoulos
    • , Stephen D. Thorpe
    •  & Armando E. del Río Hernández

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